SCHEMBL10548598

SCHEMBL10548598

O=S(=O)(c1cccc2nc(-c3ccc(O)cc3)c(-c3ccc(O)cc3)nc12)c1cccc2nc(-c3ccc(O)cc3)c(-c3ccc(O)cc3)nc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
DHODH Q02127 1/20 0.41
PIK3CG P48736 2/20 0.39
MAPT P10636 2/20 0.38
ALDH1A1 P00352 2/20 0.38
POLB P06746 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
ALPL P05186 1/20 0.37
ALPI P09923 1/20 0.37
ALPG P10696 1/20 0.37
DNMT1 P26358 1/20 0.37
MCL1 Q07820 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PARP1 P09874 2/20 0.37
TNKS O95271 1/20 0.37
GUSB P08236 1/20 0.37
TNKS2 Q9H2K2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10545516 0.85 PIK3CG (0.49) MEN1KMT2APIK3CGMAPTALDH1A1
SCHEMBL10547575 0.78 MEN1 (0.61) MEN1KMT2ADHODHPIK3CGMAPT
SCHEMBL8407200 0.78 ALDH1A1 (0.58) MEN1KMT2ADHODHMAPTALDH1A1
SCHEMBL10547343 0.76 MEN1 (0.54) MEN1KMT2ADHODHPIK3CGMAPT
SCHEMBL13172436 0.76 MEN1 (0.58) MEN1KMT2ADHODHPIK3CGMAPT
SCHEMBL8672719 0.76 MEN1 (0.58) MEN1KMT2ADHODHPIK3CGMAPT
SCHEMBL13173702 0.75 MEN1 (0.53) MEN1KMT2ADHODHPIK3CGMAPT
SCHEMBL19789815 0.75 MEN1 (0.53) MEN1KMT2ADHODHPIK3CGMAPT
SCHEMBL8407376 0.74 KMT2A (0.71) MEN1KMT2ADHODHMAPTALDH1A1
SCHEMBL10547979 0.74 MEN1 (0.56) MEN1KMT2ADHODHPIK3CGMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4797467-A COPOLYMERS WITH AROMATIC DIOLS BAYER AKTIENGESELLSCHAFT (DE) 1989-01-10 US disclosed
US-4739058-A USED IN BRANCHED POLYCARBONATES BAYER AKTIENGESELLSCHAFT (DE) 1988-04-19 US disclosed