Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.65 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.65 |
| ▸ | PPARD | Q03181 | 1/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | VDR | P11473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10546686 | 0.81 | CYSLTR1 (0.53) | GPBAR1CYSLTR1PPARDNR4A2LTB4R | |
| SCHEMBL30444017 | 0.79 | CYSLTR1 (1.00) | GPBAR1CYSLTR1KMT2A | |
| SCHEMBL422355 | 0.79 | CYSLTR1 (1.00) | GPBAR1CYSLTR1KMT2A | |
| SCHEMBL10546719 | 0.79 | CYSLTR1 (0.72) | GPBAR1CYSLTR1MRGPRX4PPARGVDR | |
| SCHEMBL10547024 | 0.79 | PDE10A (0.49) | GPBAR1CYSLTR1MRGPRX4PDE10AKMT2A | |
| SCHEMBL10919443 | 0.78 | GPBAR1 (0.47) | GPBAR1CYSLTR1PDE10A | |
| Hydrochloric Acid SCHEMBL7006935 | 0.78 | CYSLTR1 (0.97) | GPBAR1CYSLTR1KMT2A | |
| SCHEMBL10543676 | 0.77 | PDE10A (0.57) | CYSLTR1PDE10AKMT2A | |
| SCHEMBL8182867 | 0.77 | CYSLTR2 (0.80) | CYSLTR1 | |
| SCHEMBL7009714 | 0.76 | CYSLTR1 (0.70) | GPBAR1CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4631287-A | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments | USV PHARMACEUTICAL CORP. (US) | 1986-12-23 | — | — | US | claimed |
| EP-0200101-A2 | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive aliments | USV PHARMACEUTICAL CORPORATION (US) | 1986-11-05 | — | — | EP | claimed |
| US-4839369-A | ANTIINFLAMMATORY AGENTS; ANTIALLERGENS | RORER PHARMACEUTICAL CORPORATION (US) | 1989-06-13 | — | — | US | disclosed |
| US-4728668-A | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments | USV PHARMACEUTICAL CORPORATION (US) | 1988-03-01 | — | — | US | disclosed |
| US-4725619-A | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments | USV PHARMACEUTICAL CORPORATION (US) | 1988-02-16 | — | — | US | disclosed |
| US-4631287-A | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments | USV PHARMACEUTICAL CORP. (US) | 1986-12-23 | — | — | US | disclosed |
| EP-0200101-A2 | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive aliments | USV PHARMACEUTICAL CORPORATION (US) | 1986-11-05 | — | — | EP | disclosed |