Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 14/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10547607 | 0.79 | PDE10A (0.42) | GPBAR1CYSLTR1PDE10AALOX5 | |
| SCHEMBL10546022 | 0.78 | GPBAR1 (0.65) | GPBAR1CYSLTR1PDE10A | |
| SCHEMBL10547024 | 0.76 | PDE10A (0.49) | GPBAR1CYSLTR1PDE10A | |
| SCHEMBL10543676 | 0.74 | PDE10A (0.57) | CYSLTR1PDE10A | |
| SCHEMBL6269837 | 0.71 | CYSLTR1 (0.49) | GPBAR1CYSLTR1PDE10AALOX5PDE4D | |
| SCHEMBL8182867 | 0.70 | CYSLTR2 (0.80) | CYSLTR1 | |
| SCHEMBL10543161 | 0.69 | CYSLTR1 (0.74) | GPBAR1CYSLTR1PDE10AALOX5 | |
| SCHEMBL3277356 | 0.69 | PDE10A (0.61) | PDE10A | |
| SCHEMBL9828545 | 0.69 | CYSLTR1 (0.71) | GPBAR1CYSLTR1ALOX5 | |
| SCHEMBL4388489 | 0.69 | PDE10A (0.79) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200101-A2 | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive aliments | USV PHARMACEUTICAL CORPORATION (US) | 1986-11-05 | — | — | EP | disclosed |