Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10553853 | 0.95 | ALOX5 (0.49) | ALOX5EPHX1GRM2ALDH1A1SPHK1 | |
| SCHEMBL10548231 | 0.94 | ALOX5 (0.48) | ALOX5EPHX1GRM2ALDH1A1SPHK1 | |
| SCHEMBL10554476 | 0.94 | ALOX5 (0.48) | ALOX5EPHX1GRM2ALDH1A1SPHK1 | |
| SCHEMBL10552488 | 0.94 | ALOX5 (0.48) | ALOX5EPHX1GRM2ALDH1A1SPHK1 | |
| SCHEMBL10551823 | 0.91 | ALOX5 (0.52) | ALOX5ALDH1A1CYP2C9 | |
| SCHEMBL10549411 | 0.87 | ALOX5 (0.49) | ALOX5EPHX1GRM2ALDH1A1SPHK1 | |
| SCHEMBL10550991 | 0.87 | ALOX5 (0.56) | ALOX5EPHX1ALDH1A1SPHK1 | |
| SCHEMBL10548583 | 0.87 | ALOX5 (0.49) | ALOX5EPHX1ALDH1A1SPHK1CYP3A4 | |
| SCHEMBL10550926 | 0.87 | ALOX5 (0.49) | ALOX5EPHX1GRM2ALDH1A1SPHK1 | |
| SCHEMBL10551760 | 0.86 | ALOX5 (0.48) | ALOX5EPHX1GRM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4818431-A | ELECTROOPTICAL DISPLAY ELEMENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-04-04 | — | — | US | disclosed |
| EP-0117476-B1 | TETRAHYDROPYRANES | MERCK PATENT GmbH (DE) | 1987-09-16 | — | — | EP | disclosed |
| EP-0117476-A1 | Tetrahydropyranes | MERCK PATENT GmbH (DE) | 1984-09-05 | — | — | EP | disclosed |