Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18814354 | 0.90 | SLC7A5 (0.42) | CALCRLCALCA | |
| SCHEMBL22774420 | 0.90 | SLC7A5 (0.42) | CALCRLCALCA | |
| SCHEMBL140133 | 0.90 | SLC7A5 (0.42) | CALCRLCALCA | |
| Hydrochloric Acid SCHEMBL22773984 | 0.89 | SLC7A5 (0.41) | CALCRLCALCA | |
| Hydrochloric Acid SCHEMBL22773983 | 0.89 | SLC7A5 (0.41) | CALCRLCALCA | |
| Hydrochloric Acid SCHEMBL31180181 | 0.89 | SLC7A5 (0.41) | CALCRLCALCA | |
| SCHEMBL4855681 | 0.87 | CALCRL (0.42) | CALCRLCALCA | |
| SCHEMBL107000 | 0.87 | CALCA (0.39) | CALCRLCALCA | |
| SCHEMBL22796447 | 0.87 | CALCA (0.39) | CALCRLCALCA | |
| SCHEMBL3591408 | 0.87 | CALCA (0.39) | CALCRLCALCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481546-B2 | CGRP receptor antagonist | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-07-09 | — | — | US | disclosed |
| US-20120059017-A1 | CGRP Receptor Antagonist | BRISTOL-MYERS SQUIBB COMPANY | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059017-A1 | CGRP Receptor Antagonist | CALCRL, PTGIR, CALCR | CALCRL 1/4885CALCA 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.