Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.45 |
| ▸ | FLT4 | P35916 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10548813 | 0.88 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10HTT | |
| SCHEMBL5416374 | 0.87 | KMT2A (0.52) | ALDH1A1KDM4EHPGDHSD17B10HTT | |
| SCHEMBL10549291 | 0.87 | KMT2A (0.49) | ALDH1A1KDM4EHPGDHSD17B10HTT | |
| SCHEMBL3236130 | 0.85 | KMT2A (0.48) | ALDH1A1KDM4EHPGDHSD17B10HTT | |
| SCHEMBL10549552 | 0.85 | KMT2A (0.47) | ALDH1A1KDM4EHPGDHSD17B10HTT | |
| SCHEMBL10414338 | 0.84 | KMT2A (0.48) | ALDH1A1KDM4EHPGDHSD17B10HTT | |
| SCHEMBL10551689 | 0.83 | KMT2A (0.48) | ALDH1A1KDM4EHPGDHSD17B10HTT | |
| SCHEMBL7228651 | 0.83 | MAPT (0.46) | ALDH1A1KDM4EHPGDHSD17B10HTT | |
| SCHEMBL11283380 | 0.82 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10HTT | |
| SCHEMBL7229828 | 0.82 | MAPT (0.45) | ALDH1A1KDM4EHPGDHSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4851535-A | 2-(5-FLUORONICOTINOYL)ACETIC ACID DERIVATIVES, ANTIBACTERIAL 1-ARYL-1,4-DIHYDRO-4-OXONAPHTHYRIDINES | TOYAMA CHEMICAL CO., LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| US-4704459-A | VILSMEIER REAGENT | TOYAMA CHEMICAL CO., LTD. (JP) | 1987-11-03 | — | — | US | disclosed |