Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.50 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
| ▸ | TOP1 | P11387 | 9/20 | 0.48 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9689732 | 0.99 | KCNH2 (0.51) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL10509057 | 0.91 | KDM4E (0.51) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL10684793 | 0.91 | KCNH2 (0.51) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL10369147 | 0.89 | KCNH2 (0.49) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL10683743 | 0.87 | POLB (0.52) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9688244 | 0.87 | KCNH2 (0.47) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9688756 | 0.87 | FOXO1 (0.49) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9689834 | 0.87 | KCNH2 (0.47) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9688393 | 0.87 | FOXO1 (0.48) | KCNH2CACNA1FPOLBMAPK1CACNA1D | |
| SCHEMBL9687744 | 0.87 | KCNH2 (0.47) | KCNH2CACNA1FPOLBMAPK1CACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4822801-A | 4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivative as antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1989-04-18 | — | — | US | claimed |