Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10545443 | 0.99 | S1PR1 (0.39) | S1PR1SLC6A3SLC6A4S1PR3TACR1 | |
| SCHEMBL10546672 | 0.97 | S1PR1 (0.38) | S1PR1SLC6A3SLC6A4S1PR3TACR1 | |
| SCHEMBL10547270 | 0.95 | TACR1 (0.38) | S1PR1SLC6A4TACR1SLC6A2NR1I2 | |
| SCHEMBL10547558 | 0.88 | LTA4H (0.39) | S1PR1SLC6A3SLC6A4S1PR3TACR1 | |
| SCHEMBL10550785 | 0.87 | LTA4H (0.39) | S1PR1SLC6A3SLC6A4S1PR3TACR1 | |
| SCHEMBL9558579 | 0.85 | LTA4H (0.39) | S1PR1SLC6A3SLC6A4TACR1SLC6A2 | |
| SCHEMBL9558575 | 0.82 | LTA4H (0.41) | SLC6A3SLC6A4TACR1SLC6A2 | |
| SCHEMBL9558016 | 0.82 | LPAR1 (0.34) | NR1I2HSD11B1 | |
| SCHEMBL10811296 | 0.82 | LPAR1 (0.34) | NR1I2HSD11B1 | |
| SCHEMBL10546150 | 0.78 | FFAR4 (0.44) | CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4814340-A | 1,4-diaryl alkane derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1989-03-21 | — | — | US | disclosed |
| US-4661501-A | Certain aryl-alkane-2-pyridyloxy-phenyl derivatives having insecticidal and acaricidal activity | MITSUI TOATSU CHEMICALS, INC. (JP) | 1987-04-28 | — | — | US | disclosed |