Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CD69 | Q07108 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15753790 | 0.83 | LMNA (0.53) | KMT2AALDH1A1RAB9ALMNATSHR | |
| SCHEMBL15762675 | 0.82 | CYP1A2 (0.48) | CA1CA2ALDH1A1POLBRAB9A | |
| SCHEMBL4215159 | 0.82 | CA1 (0.59) | KMT2ACA1CA2ALDH1A1POLB | |
| SCHEMBL2554736 | 0.79 | PTGDR2 (0.62) | PTGDR2KMT2ACD69CA1CA2 | |
| SCHEMBL9774310 | 0.79 | POLB (0.57) | KMT2ACD69ALDH1A1POLBRAB9A | |
| SCHEMBL4746689 | 0.79 | PTGDR2 (0.57) | PTGDR2KMT2ACD69CA1CA2 | |
| SCHEMBL14042113 | 0.78 | PTGDR2 (0.55) | PTGDR2KMT2ACD69CA1CA2 | |
| SCHEMBL10695461 | 0.78 | CA1 (0.46) | CA1CA2ALDH1A1POLBRAB9A | |
| Benzene SCHEMBL28217563 | 0.76 | TSHR (0.55) | KMT2ACA1CA2ALDH1A1POLB | |
| SCHEMBL23111641 | 0.76 | PTGDR2 (0.57) | PTGDR2KMT2ACD69CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4829067-A | INHIBITORS OF REFLECTIVE CONTRACTION OF BLADDER | TANABE SEIYAKU CO., LTD. (JP) | 1989-05-09 | — | — | US | disclosed |
| EP-0270342-A2 | A benzo-furan (or -thiophene) derivative and processes for preparing the same | Tanabe Seiyaku Co., Ltd. (JP) | 1988-06-08 | — | — | EP | disclosed |