Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 18/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 17/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2283 | 0.98 | SLC6A4 (0.69) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL14277682 | 0.91 | SLC6A4 (0.68) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL4912644 | 0.91 | SLC6A4 (0.68) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL1864 | 0.89 | SLC6A4 (0.66) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL2102 | 0.86 | SLC6A4 (0.54) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL9864547 | 0.84 | SLC6A4 (0.62) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL9864280 | 0.83 | SLC6A4 (0.58) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL3519750 | 0.83 | SLC6A4 (1.00) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL7794188 | 0.83 | SLC6A4 (0.49) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL10840419 | 0.83 | SLC6A4 (0.78) | SLC6A4SLC6A3CYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4806570-A | ANTIDEPRESSANTS | THE BOOTS COMPANY PLC (GB) | 1989-02-21 | — | — | US | claimed |
| US-4522828-A | CYCLOBUTYLALKYLAMINE COMPOUNDS, ANTIDEPRESSANTS | THE BOOTS COMPANY PLC (GB) | 1985-06-11 | — | — | US | claimed |