Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 18/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 17/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14277682 | 1.00 | SLC6A4 (0.68) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL1864 | 0.98 | SLC6A4 (0.66) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL10550753 | 0.91 | SLC6A4 (0.71) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| Hydrochloric Acid SCHEMBL2283 | 0.89 | SLC6A4 (0.69) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL9864280 | 0.86 | SLC6A4 (0.58) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL9863701 | 0.85 | SLC6A4 (0.59) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL9863714 | 0.85 | SLC6A4 (0.59) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL9863885 | 0.84 | SLC6A4 (0.58) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL9864587 | 0.84 | SLC6A4 (0.57) | SLC6A4SLC6A3CYP3A4ALOX15TSHR | |
| SCHEMBL9864001 | 0.83 | SLC6A4 (0.57) | SLC6A4SLC6A3CYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214870-A1 | Method of Preparing Amine Stereoisomers | HAN ZHENGXU | 2008-09-04 | — | — | US | disclosed |
| US-7332610-B2 | Method of preparing amine stereoisomers | APSINTERM LLC (US) | 2008-02-19 | — | — | US | disclosed |
| US-20060287539-A1 | Method of preparing amine stereoisomers | HAN ZHENGXU | 2006-12-21 | — | — | US | disclosed |
| US-7129378-B2 | Method of preparing amine stereoisomers | APSINTERM, LLC (US) | 2006-10-31 | — | — | US | disclosed |
| US-20050165240-A1 | Method of preparing amine stereoisomers | APSINTERM, LLC | 2005-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050165240-A1 | Method of preparing amine stereoisomers | SRM, TST, SMOX | SLC6A4 262/4885SLC6A3 449/4885CYP3A4 730/4885 |
| US-20080214870-A1 | Method of Preparing Amine Stereoisomers | SRM, PNMT, SMS | SLC6A4 50/4885SLC6A3 150/4885CYP3A4 247/4885 |
| US-20060287539-A1 | Method of preparing amine stereoisomers | SRM, PNMT, SMS | SLC6A4 50/4885SLC6A3 150/4885CYP3A4 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.