Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.33 |
| ▸ | PTAFR | P25105 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10548762 | 0.96 | FASN (0.48) | SLC6A3FASNSLC6A2SLC6A4DRD2 | |
| SCHEMBL10548575 | 0.91 | SLC6A3 (0.41) | SLC6A3FASNSLC6A2SLC6A4DRD2 | |
| SCHEMBL10556339 | 0.90 | SLC6A3 (0.40) | SLC6A3FASNSLC6A2SLC6A4DRD2 | |
| SCHEMBL10553972 | 0.88 | GRM2 (0.40) | SLC6A3FASNSLC6A2SLC6A4DRD2 | |
| SCHEMBL10552177 | 0.88 | GRM2 (0.40) | SLC6A3FASNSLC6A2SLC6A4DRD2 | |
| SCHEMBL10551569 | 0.88 | GRM2 (0.40) | SLC6A3FASNSLC6A2SLC6A4DRD2 | |
| SCHEMBL10551691 | 0.87 | FASN (0.42) | SLC6A3FASNSLC6A2SLC6A4DRD2 | |
| SCHEMBL10547957 | 0.86 | FASN (0.42) | SLC6A3FASNSLC6A2SLC6A4DRD2 | |
| SCHEMBL16591212 | 0.86 | FASN (0.44) | SLC6A3FASNSLC6A2SLC6A4CYP2C9 | |
| SCHEMBL10551160 | 0.86 | FASN (0.44) | SLC6A3FASNSLC6A2CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4818431-A | ELECTROOPTICAL DISPLAY ELEMENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-04-04 | — | — | US | disclosed |
| EP-0117476-B1 | TETRAHYDROPYRANES | MERCK PATENT GmbH (DE) | 1987-09-16 | — | — | EP | disclosed |
| EP-0117476-A1 | Tetrahydropyranes | MERCK PATENT GmbH (DE) | 1984-09-05 | — | — | EP | disclosed |