Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10553210 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TSHRHTTCYP2C19CYP1A2 | |
| SCHEMBL1596824 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TSHRHTTCYP2C19CYP1A2 | |
| SCHEMBL616174 | 0.90 | ALDH1A1 (0.57) | ALDH1A1TSHRHTTCYP2C19CYP1A2 | |
| SCHEMBL7943831 | 0.85 | CYP2C19 (0.58) | ALDH1A1TSHRCYP2C19CYP1A2CYP2C9 | |
| SCHEMBL9284492 | 0.85 | ALDH1A1 (0.49) | ALDH1A1TSHRHTTCYP2C19CYP1A2 | |
| SCHEMBL10358475 | 0.82 | TSHR (0.50) | ALDH1A1TSHRHTTCYP2C19CYP1A2 | |
| SCHEMBL15436344 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRHTTCYP2C19CYP1A2 | |
| SCHEMBL11032404 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TSHRHTTCYP2C19CYP1A2 | |
| SCHEMBL12076544 | 0.81 | ALDH1A1 (0.49) | ALDH1A1TSHRHTTCYP2C19CYP1A2 | |
| SCHEMBL9365960 | 0.80 | ALDH1A1 (0.38) | ALDH1A1TSHRHTTMAPTACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4876353-A | Process for the preparation of optically active 2-hydroxyethyl-azole derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-24 | — | — | US | claimed |
| EP-0277572-A2 | Process for the preparation of optically active 2-hydroxyethyl-azole derivatives | BAYER AG (DE) | 1988-08-10 | — | — | EP | claimed |
| US-4876353-A | Process for the preparation of optically active 2-hydroxyethyl-azole derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-24 | — | — | US | disclosed |
| EP-0277572-A2 | Process for the preparation of optically active 2-hydroxyethyl-azole derivatives | BAYER AG (DE) | 1988-08-10 | — | — | EP | disclosed |