Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10554749 | 1.00 | TSHR (0.55) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL1129862 | 0.87 | TSHR (0.47) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL6396178 | 0.87 | TSHR (0.47) | TSHRALDH1A1TDP1SMN1; SMN2MAPK1 | |
| SCHEMBL14961579 | 0.86 | TSHR (0.38) | TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL14961600 | 0.86 | TSHR (0.38) | TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL14961597 | 0.86 | TSHR (0.38) | TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL14961573 | 0.86 | TSHR (0.38) | TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL14961577 | 0.86 | TSHR (0.38) | TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL14961580 | 0.86 | TSHR (0.38) | TSHRALDH1A1TDP1SMN1; SMN2 | |
| SCHEMBL14961596 | 0.86 | TSHR (0.38) | TSHRALDH1A1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4889953-A | ANTITUMOR AND -CARCINOGENIC AGENTS; PLATELET ACTIVATING FACTOR ANTAGONIST; CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-12-26 | — | — | US | disclosed |
| EP-0254540-A2 | Glycerol derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-01-27 | — | — | EP | disclosed |