SCHEMBL6396178

SCHEMBL6396178

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)CCOCC1CO1

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.42
ALDH1A1 P00352 3/20 0.40
TDP1 Q9NUW8 1/20 0.40
MAPK1 P28482 1/20 0.39
GBA1 P04062 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1129862 1.00 TSHR (0.47) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL24388690 0.98 TSHR (0.48) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL5371037 0.97 TSHR (0.44) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL1830506 0.90 TSHR (0.39) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL10552004 0.87 TSHR (0.55) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL10554749 0.87 TSHR (0.55) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL19615496 0.85 TSHR (0.46) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL20746137 0.84 TSHR (0.33) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1
SCHEMBL14961587 0.83 LMNA (0.35) TSHRSMN1; SMN2ALDH1A1
SCHEMBL10782972 0.82 TSHR (0.45) TSHRSMN1; SMN2ALDH1A1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111548654-B Durable ceramic antifouling liquid and using method thereof 清远市宏图助剂有限公司 2022-07-29 CN disclosed
CN-111548654-A Durable ceramic antifouling liquid and using method thereof 清远市宏图助剂有限公司 2020-08-18 CN disclosed
US-6906167-B2 Metathesis ring-opening polymerization using epoxides; using rare earth metal catalyst and reducing agent KAO CORPORATION (JP) 2005-06-14 US disclosed
US-20050004344-A1 Process for producing polyether KAO CORPORATION (JP) 2005-01-06 US disclosed
US-6800723-B2 EPOXY RESINS FORMED VIA CATALYTIC METHATHESIS RING-OPENING POLYMERIZATION WITH RARE EARTH METAL COMPLEX KAO CORPORATION (JP) 2004-10-05 US disclosed
EP-1057845-B1 PROCESS FOR PRODUCING POLYETHER KAO CORP (JP) 2004-01-21 EP disclosed
US-20020151674-A1 Epoxy resins formed via catalytic methathesis ring-opening polymerization with rare earth metal complex KAO CORPORATION (JP) 2002-10-17 US disclosed
US-6417323-B1 RING-OPENING POLYMERIZATION OF SUBSTITUTED EPOXIDE IN RARE EARTH COMPOUND AND REDUCING AGENT PRESENCE; ETHERIFICATION KAO CORPORATION (JP) 2002-07-09 US disclosed
EP-1057845-A1 PROCESS FOR PRODUCING POLYETHER Kao Corporation (JP) 2000-12-06 EP disclosed