Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10557718 | 0.82 | TDP1 (0.51) | MRGPRX4TDP1POLBSMN1; SMN2MAOB | |
| SCHEMBL10555079 | 0.82 | NR4A2 (0.56) | MRGPRX4MAOBMAOANR4A2 | |
| SCHEMBL10562286 | 0.82 | MAOB (0.51) | MAOBTSHR | |
| SCHEMBL11933660 | 0.81 | TSHR (0.56) | TDP1POLBSMN1; SMN2TSHRKDM4E | |
| SCHEMBL11925272 | 0.77 | TSHR (0.52) | TDP1POLBSMN1; SMN2TSHRKDM4E | |
| SCHEMBL1470290 | 0.77 | TSHR (0.52) | TDP1POLBSMN1; SMN2TSHRKDM4E | |
| SCHEMBL3982478 | 0.77 | SMN1; SMN2 (0.44) | MRGPRX4TDP1POLBSMN1; SMN2MAOB | |
| SCHEMBL14973111 | 0.77 | PAX8 (0.47) | MRGPRX4TDP1POLBSMN1; SMN2MAOB | |
| SCHEMBL1957290 | 0.77 | KDM4E (0.49) | TDP1POLBSMN1; SMN2TSHRKDM4E | |
| SCHEMBL11455143 | 0.77 | SMN1; SMN2 (0.54) | TDP1POLBSMN1; SMN2TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4889858-A | ANTIHYPOXIC AGENTS, ANTICONVULSANTS, LIPID PEROXIDATION INHIBITORS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1989-12-26 | — | — | US | disclosed |
| EP-0269755-A1 | DIBENZ b,e OXEPIN DERIVATIVE AND PHARMACEUTICAL CONTAINING THE SAME AS ACTIVE INGREDIENT | Dainippon Pharmaceutical Co., Ltd. (JP) | 1988-06-08 | — | — | EP | disclosed |