Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 4/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6473252 | 0.85 | CASR (0.50) | CASRMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL11201464 | 0.85 | KMT2A (0.54) | MEN1KMT2AKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL5782693 | 0.84 | MEN1 (0.58) | MEN1KMT2ARAB9ATDP1BACE1 | |
| SCHEMBL10552234 | 0.80 | AKR1C3 (0.49) | MEN1KMT2AFFAR1TDP1ALDH1A1 | |
| SCHEMBL28519052 | 0.79 | MEN1 (0.51) | MEN1KMT2ATDP1BACE1 | |
| SCHEMBL2274629 | 0.77 | PTPN5 (0.69) | CASRPTPN5FFAR1HDAC4 | |
| SCHEMBL2274622 | 0.77 | PTPN5 (0.69) | CASRPTPN5FFAR1HDAC4 | |
| SCHEMBL2274626 | 0.77 | PTPN5 (0.69) | CASRPTPN5FFAR1HDAC4 | |
| SCHEMBL27962430 | 0.77 | NPSR1 (0.68) | CASRKDM4ENPC1HPGDRAB9A | |
| SCHEMBL13247934 | 0.77 | NR1H4 (0.63) | KDM4ENPC1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4866062-A | TREATMENT OF DISEASES ARISING FROM A HYPOFUNCTION OF THE DOPAMINERGIC SYSTEM | RICHTER GEDEON VEGYESZETI GYAR (HU) | 1989-09-12 | — | — | US | disclosed |