SCHEMBL105531

SCHEMBL105531

O=c1ccc(Br)c[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11704548 0.97
SCHEMBL11166857 0.80 ALDH1A1 (0.67)
SCHEMBL269266 0.67 ALDH1A1 (0.50)
SCHEMBL22322700 0.67 ALDH1A1 (0.50)
SCHEMBL6931003 0.67
SCHEMBL22298049 0.67
SCHEMBL2011066 0.67
SCHEMBL3371230 0.67
SCHEMBL629361 0.67
SCHEMBL3405485 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 935 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113354631-B 1,3,4-oxadiazole derivative and preparation method and application thereof 江苏大学 2022-11-18 CN claimed
CN-113354631-A 1,3, 4-oxadiazole derivative and preparation method and application thereof 江苏大学 2021-09-07 CN claimed
EP-0487602-A4 5-(1-AMINOCYCLOHEXYL)-2(1H)-PYRIDINONE AND RELATED COMPOUNDS 1993-03-17 EP claimed
EP-0487602-A1 5-(1-AMINOCYCLOHEXYL)-2(1H)-PYRIDINONE AND RELATED COMPOUNDS. HOECHST ROUSSEL PHARMA (US) 1992-06-03 EP claimed
WO-1991002721-A1 5-(1-AMINOCYCLOHEXYL)-2(1H)-PYRIDINONE AND RELATED COMPOUNDS HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1991-03-07 WO claimed
JP-9100288-A None JP disclosed
CN-122036680-A Anti-fibrotic pyridones 英特穆恩公司 2026-05-15 CN disclosed
WO-2026090477-A1 HELICASE INHIBITORS AND USES THEREOF KIMIA THERAPEUTICS, INC. (US) 2026-04-30 WO disclosed
US-20260091048-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-02 US disclosed
EP-4709720-A1 INHIBITORS AND DEGRADERS OF PIP4K PROTEIN Larkspur Biosciences, Inc. (US) 2026-03-18 EP disclosed
EP-4665733-A1 AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 Bristol-Myers Squibb Company (US) 2025-12-24 EP disclosed
WO-2025215121-A1 HEDGEHOG ACYLTRANSFERASE INHIBITORS IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2025-10-16 WO disclosed
WO-1993007137-A1 PYRIDINOL DERIVATIVES AS MEDICAMENTS SMITHKLINE BEECHAM PLC (GB) 1993-04-15 WO disclosed
EP-0487602-A4 5-(1-AMINOCYCLOHEXYL)-2(1H)-PYRIDINONE AND RELATED COMPOUNDS 1993-03-17 EP disclosed
EP-0487602-A1 5-(1-AMINOCYCLOHEXYL)-2(1H)-PYRIDINONE AND RELATED COMPOUNDS. HOECHST ROUSSEL PHARMA (US) 1992-06-03 EP disclosed
US-5112981-A Analgesics, treatment of Alzheimer*s disease HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1992-05-12 US disclosed
US-5039809-A 5-(1-aminocyclohexyl)-2(1H)-pyridinone and related compounds HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1991-08-13 US disclosed
WO-1991002721-A1 5-(1-AMINOCYCLOHEXYL)-2(1H)-PYRIDINONE AND RELATED COMPOUNDS HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1991-03-07 WO disclosed
US-4978663-A Analgesics; cognition activators HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1990-12-18 US disclosed
US-4092321-A Process for the preparation of imidazo [1,2-a] pyridines MERCK & CO., INC. (US) 1978-05-30 US disclosed