Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20819716 | 0.79 | TSHR (0.50) | TSHRNR5A1SMPD1PLA2G2ATP53 | |
| SCHEMBL9167272 | 0.79 | TSHR (0.50) | TSHRNR5A1SMPD1PLA2G2ATP53 | |
| SCHEMBL1664744 | 0.79 | TSHR (0.50) | TSHRNR5A1SMPD1PLA2G2ATP53 | |
| SCHEMBL1669927 | 0.79 | TSHR (0.50) | TSHRNR5A1SMPD1PLA2G2ATP53 | |
| SCHEMBL1452222 | 0.79 | TSHR (0.50) | TSHRNR5A1SMPD1PLA2G2ATP53 | |
| SCHEMBL10474244 | 0.79 | TSHR (0.50) | TSHRNR5A1SMPD1PLA2G2ATP53 | |
| SCHEMBL2092766 | 0.79 | TSHR (0.50) | TSHRNR5A1SMPD1PLA2G2ATP53 | |
| SCHEMBL20819713 | 0.79 | TSHR (0.50) | TSHRNR5A1SMPD1PLA2G2ATP53 | |
| SCHEMBL920552 | 0.78 | TSHR (0.49) | TSHRNR5A1SMPD1PLA2G2ATP53 | |
| SCHEMBL9700131 | 0.78 | TSHR (0.49) | TSHRNR5A1SMPD1PLA2G2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7988570-B2 | Multi-layer core golf ball having opposing hardness gradient with steep gradient outer core layer | ACUSHNET COMPANY (US) | 2011-08-02 | — | — | US | disclosed |
| US-20110014999-A1 | MULTI-LAYER CORE GOLF BALL HAVING OPPOSING HARDNESS GRADIENT WITH STEEP GRADIENT OUTER CORE LAYER | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2011-01-20 | — | — | US | disclosed |