SCHEMBL1669927

SCHEMBL1669927

CCCCCCCCCCCCCCCCCCOc1cc[c]c(C)c1

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
NR5A1 Q13285 1/20 0.47
PLA2G2A P14555 1/20 0.42
TP53 P04637 1/20 0.42
SMPD1 P17405 3/20 0.42
LTA4H P09960 3/20 0.42
PLA2G4B P0C869 1/20 0.41
THRA P10827 1/20 0.41
THRB P10828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10474244 1.00 TSHR (0.50) TSHRNR5A1PLA2G2ATP53SMPD1
SCHEMBL161799 0.93 LTA4H (0.43) TSHRNR5A1LTA4H
SCHEMBL160643 0.87 KMT2A (0.41) TSHRLTA4H
SCHEMBL27647098 0.84 PDIA6 (0.34) TSHRTP53
SCHEMBL2092766 0.83 TSHR (0.50) TSHRNR5A1PLA2G2ATP53SMPD1
SCHEMBL1664744 0.83 TSHR (0.50) TSHRNR5A1PLA2G2ATP53SMPD1
SCHEMBL20819716 0.83 TSHR (0.50) TSHRNR5A1PLA2G2ATP53SMPD1
SCHEMBL20819713 0.83 TSHR (0.50) TSHRNR5A1PLA2G2ATP53SMPD1
SCHEMBL1452222 0.83 TSHR (0.50) TSHRNR5A1PLA2G2ATP53SMPD1
SCHEMBL9167272 0.83 TSHR (0.50) TSHRNR5A1PLA2G2ATP53SMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7897664-B2 Pneumatic tire THE GOODYEAR TIRE & RUBBER COMPANY (US) 2011-03-01 US claimed
US-20100076126-A1 PNEUMATIC TIRE THE GOODYEAR TIRE & RUBBER COMPANY 2010-03-25 US claimed
US-20090082495-A1 Pneumatic Tire ZIMMER RENE JEAN 2009-03-26 US claimed
EP-2485900-B1 MULTICOLOUR THERMAL IMAGING MATERIAL ZINK IMAGING INC (US) 2014-05-21 EP disclosed
US-8372782-B2 Imaging system ZINK IMAGING, INC. (US) 2013-02-12 US disclosed
EP-2485900-A1 MULTICOLOUR THERMAL IMAGING MATERIAL Zink Imaging, Inc. (US) 2012-08-15 EP disclosed
EP-1597084-B1 IMAGING SYSTEM ZINK IMAGING LLC (US) 2012-04-11 EP disclosed
WO-2011044049-A1 MULTICOLOUR THERMAL IMAGING MATERIAL ZINK IMAGING, INC. (US) 2011-04-14 WO disclosed
US-7897664-B2 Pneumatic tire THE GOODYEAR TIRE & RUBBER COMPANY (US) 2011-03-01 US disclosed
US-20100099556-A1 Imaging System ZINK IMAGING, INC. 2010-04-22 US disclosed
US-20100076126-A1 PNEUMATIC TIRE THE GOODYEAR TIRE & RUBBER COMPANY 2010-03-25 US disclosed
US-20100016154-A1 IMAGING SYSTEM ZINK IMAGING, INC. 2010-01-21 US disclosed
US-20090082495-A1 Pneumatic Tire ZIMMER RENE JEAN 2009-03-26 US disclosed
US-7504360-B2 Imaging system ZINK IMAGING, INC. (US) 2009-03-17 US disclosed
US-20070123421-A1 Imaging system ZINK IMAGING, LLC. 2007-05-31 US disclosed
US-7176161-B2 Containing crystalline compounds which produce color when thermally converted to liquid or amorphous form time-independent ZINK IMAGING, LLC (US) 2007-02-13 US disclosed
EP-1597084-A2 IMAGING SYSTEM Polaroid Corporation (US) 2005-11-23 EP disclosed
WO-2004078479-A2 IMAGING SYSTEM POLAROID CORPORATION (US) 2004-09-16 WO disclosed
US-20040176248-A1 Imaging system ZINK HOLDINGS LLC 2004-09-09 US disclosed