Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.69 |
| ▸ | MC4R | P32245 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855234 | 0.85 | SIGMAR1 (0.69) | SIGMAR1MC4RLMNAPOLBDRD4 | |
| SCHEMBL2489199 | 0.83 | SIGMAR1 (1.00) | SIGMAR1MC4RLMNAPOLBDRD4 | |
| SCHEMBL576868 | 0.83 | SIGMAR1 (1.00) | SIGMAR1MC4RLMNAPOLBDRD4 | |
| SCHEMBL242970 | 0.83 | SIGMAR1 (1.00) | SIGMAR1MC4RLMNAPOLBDRD4 | |
| SCHEMBL8188324 | 0.83 | SIGMAR1 (1.00) | SIGMAR1MC4RLMNAPOLBDRD4 | |
| SCHEMBL1041303 | 0.83 | SIGMAR1 (1.00) | SIGMAR1MC4RLMNAPOLBDRD4 | |
| SCHEMBL1415730 | 0.83 | SIGMAR1 (1.00) | SIGMAR1MC4RLMNAPOLBDRD4 | |
| Hydrochloric Acid SCHEMBL4074661 | 0.83 | SIGMAR1 (0.67) | SIGMAR1MC4RLMNAPOLBDRD4 | |
| Water SCHEMBL8695926 | 0.81 | SIGMAR1 (0.95) | SIGMAR1MC4RLMNAPOLBDRD4 | |
| SCHEMBL13036529 | 0.81 | SIGMAR1 (0.69) | SIGMAR1MC4RLMNAPOLBDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4801706-A | ANTIARRHYTHMIA HYPOTENSIVE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |