Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10554199 | 1.00 | RAB9A (0.44) | RAB9ALMNACRBNNPC1MAOA | |
| SCHEMBL10554197 | 1.00 | RAB9A (0.44) | RAB9ALMNACRBNNPC1MAOA | |
| SCHEMBL10552672 | 0.98 | RAB9A (0.42) | RAB9ALMNACRBNNPC1MAOA | |
| SCHEMBL10552667 | 0.98 | RAB9A (0.42) | RAB9ALMNACRBNNPC1MAOA | |
| SCHEMBL10552678 | 0.98 | RAB9A (0.42) | RAB9ALMNACRBNNPC1MAOA | |
| SCHEMBL10550561 | 0.96 | RAB9A (0.44) | RAB9ALMNACRBNNPC1MAOA | |
| SCHEMBL10550555 | 0.96 | RAB9A (0.44) | RAB9ALMNACRBNNPC1MAOA | |
| SCHEMBL10550549 | 0.96 | RAB9A (0.44) | RAB9ALMNACRBNNPC1MAOA | |
| SCHEMBL10555737 | 0.94 | RAB9A (0.43) | RAB9ALMNACRBNNPC1MAOA | |
| SCHEMBL10555725 | 0.94 | RAB9A (0.43) | RAB9ALMNACRBNNPC1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215120-B1 | CYCLOHEXANE DERIVATIVES | MERCK PATENT GmbH (DE) | 1989-08-23 | — | — | EP | disclosed |
| US-4846998-A | LIQUID CRYSTALS, ESTERS, NITRILES; ETHERS, HYDROCARBONS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-07-11 | — | — | US | disclosed |
| EP-0215120-A1 | CYCLOHEXANE DERIVATIVES. | MERCK PATENT GMBH (DE) | 1987-03-25 | — | — | EP | disclosed |
| WO-1986005486-A1 | CYCLOHEXANE DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-09-25 | — | — | WO | disclosed |