SCHEMBL10554235

SCHEMBL10554235

CCCC1CCC(c2ccc(C(=O)O)cc2)C1

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.62
ALDH1A1 P00352 2/20 0.59
LMNA P02545 1/20 0.59
MAPT P10636 1/20 0.59
MEN1 O00255 1/20 0.52
MAPK1 P28482 1/20 0.52
KMT2A Q03164 1/20 0.52
CYP2D6 P10635 2/20 0.42
RAB9A P51151 1/20 0.39
AKR1C3 P42330 1/20 0.38
AKR1C1 Q04828 1/20 0.38
DGAT1 O75907 1/20 0.38
MRGPRX4 Q96LA9 1/20 0.37
RARB P10826 1/20 0.37
RARG P13631 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6457428 0.92 CYP2C9 (0.57) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL6457433 0.92 CYP2C9 (0.57) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL3267992 0.91 CYP2C9 (0.75) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL2770921 0.91 CYP2C9 (0.75) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL10557079 0.88 CYP2C9 (0.62) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL10557084 0.88 CYP2C9 (0.62) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL10552046 0.88 CYP2C9 (0.62) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL10557076 0.88 CYP2C9 (0.62) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL7722697 0.87 CYP2C9 (0.69) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL7722695 0.87 CYP2C9 (0.69) CYP2C9ALDH1A1LMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4873019-A LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1989-10-10 US disclosed