Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 2/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6457433 | 1.00 | CYP2C9 (0.57) | CYP2C9LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL6453878 | 0.92 | CYP2C9 (0.48) | CYP2C9LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL6453874 | 0.92 | CYP2C9 (0.48) | CYP2C9LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL10554235 | 0.92 | CYP2C9 (0.62) | CYP2C9LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL6459121 | 0.91 | CYP2C9 (0.47) | CYP2C9LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL6459117 | 0.91 | CYP2C9 (0.47) | CYP2C9LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL6454612 | 0.90 | CYP2C9 (0.46) | CYP2C9LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL6454611 | 0.90 | CYP2C9 (0.46) | CYP2C9LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL6461442 | 0.90 | CYP2C9 (0.46) | CYP2C9LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL6461439 | 0.90 | CYP2C9 (0.46) | CYP2C9LMNAALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6913797-B1 | Decahydronaphthalene derivative | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2005-07-05 | — | — | US | disclosed |
| EP-1108700-A1 | DECAHYDRONAPHTHALENE DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2001-06-20 | — | — | EP | disclosed |