Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13555632 | 0.98 | — | — | |
| SCHEMBL10878756 | 0.95 | SLC22A6 (0.35) | SLC22A6GABRR1LMNACACNA2D1CACNB3 | |
| SCHEMBL11160781 | 0.95 | SLC22A6 (0.35) | SLC22A6GABRR1LMNACACNA2D1CACNB3 | |
| SCHEMBL3773162 | 0.79 | — | — | |
| SCHEMBL11121195 | 0.77 | — | — | |
| SCHEMBL17053634 | 0.76 | TSHR (0.39) | LMNAMMP1MMP2MMP3MMP9 | |
| SCHEMBL10554238 | 0.76 | CA2 (0.44) | — | |
| SCHEMBL11160758 | 0.76 | CA2 (0.44) | — | |
| SCHEMBL10878751 | 0.76 | CA2 (0.44) | — | |
| SCHEMBL11914187 | 0.74 | MAPT (0.33) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4824969-A | USING CATALYTIC MIXTURES OF AN OSMIUM COMPOUND, A COPPER COMPOUND AND AN N-HETEROCYCLIC COMPOUND; PROCESS CONTROL | EXXON RESEARCH & ENGINEERING CO. (US) | 1989-04-25 | — | — | US | disclosed |
| EP-0160148-A1 | Process for the hydroxylation of olefins using molecular oxygen, an osmium containing catalyst, a copper cocatalyst, and a cycloaliphatic amine based promoter | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1985-11-06 | — | — | EP | disclosed |
| EP-0139498-A1 | Process for the hydroxylation of olefins using molecular oxygen, an osmium containing catalyst, a copper co-catalyst, and an aromatic amine based promoter | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1985-05-02 | — | — | EP | disclosed |
| US-4496779-A | Process for the hydroxylation of olefins using molecular oxygen, an osmium containing catalyst, a copper co-catalyst, and a cycloaliphatic amine based promoter | EXXON RESEARCH & ENGINEERING CO. (US) | 1985-01-29 | — | — | US | disclosed |
| US-4496778-A | Process for the hydroxylation of olefins using molecular oxygen, an osmium containing catalyst, a copper Co-catalyst, and an aromatic amine based promoter | EXXON RESEARCH & ENGINEERING CO. (US) | 1985-01-29 | — | — | US | disclosed |