Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 8/20 | 0.58 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10555224 | 0.93 | PTGIR (0.53) | PTGIRTBXAS1KDM4CTBXA2R | |
| SCHEMBL10550905 | 0.92 | PTGIR (0.52) | PTGIRTBXAS1KDM4CPTGDR2ALDH1A1 | |
| SCHEMBL10551008 | 0.92 | PTGIR (0.52) | PTGIRTBXAS1KDM4CPTGDR2TBXA2R | |
| SCHEMBL10555708 | 0.92 | PTGIR (0.49) | PTGIRTBXAS1KDM4CGBA1HTR6 | |
| SCHEMBL10550942 | 0.90 | PTGIR (0.51) | PTGIRTBXAS1KDM4CPTGDR2HTR6 | |
| SCHEMBL10550823 | 0.90 | PTGIR (0.50) | PTGIRTBXAS1KDM4CPTGDR2TBXA2R | |
| SCHEMBL10550186 | 0.88 | PTGIR (0.50) | PTGIRTBXAS1KDM4CPTGDR2TBXA2R | |
| SCHEMBL10552741 | 0.84 | HTR6 (0.44) | PTGIRKDM4CTBXA2RHTR6 | |
| SCHEMBL10553610 | 0.83 | PTGIR (0.43) | PTGIRTBXAS1KDM4CHTR6ALDH1A1 | |
| SCHEMBL10357606 | 0.83 | PTGIR (0.52) | PTGIRTBXAS1PTGDR2TBXA2RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4886898-A | THROMOBOXANE ANTAGONISTS | BAYER AKTIENGESELLSCHAFT (DE) | 1989-12-12 | — | — | US | disclosed |
| US-4868332-A | ANTITHROMBOTIC, ANTIATHEROSCLEROTIC, ANTIISCHEMIC | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-19 | — | — | US | disclosed |