Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.59 |
| ▸ | SPHK1 | Q9NYA1 | 15/20 | 0.58 |
| ▸ | SPHK2 | Q9NRA0 | 10/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10551973 | 1.00 | ALOX5 (0.59) | ALOX5SPHK1SPHK2THRATHRB | |
| SCHEMBL10550421 | 1.00 | ALOX5 (0.59) | ALOX5SPHK1SPHK2THRATHRB | |
| SCHEMBL10553939 | 0.99 | ALOX5 (0.60) | ALOX5SPHK1SPHK2THRATHRB | |
| SCHEMBL10556368 | 0.95 | ALOX5 (0.59) | ALOX5SPHK1SPHK2THRATHRB | |
| SCHEMBL10550761 | 0.95 | ALOX5 (0.59) | ALOX5SPHK1SPHK2THRATHRB | |
| SCHEMBL10552770 | 0.95 | ALOX5 (0.59) | ALOX5SPHK1SPHK2THRATHRB | |
| SCHEMBL10555924 | 0.95 | ALOX5 (0.59) | ALOX5SPHK1SPHK2THRATHRB | |
| SCHEMBL10548516 | 0.95 | ALOX5 (0.59) | ALOX5SPHK1SPHK2THRATHRB | |
| SCHEMBL10553483 | 0.95 | ALOX5 (0.59) | ALOX5SPHK1SPHK2THRATHRB | |
| SCHEMBL10551308 | 0.95 | ALOX5 (0.59) | ALOX5SPHK1SPHK2THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4818431-A | ELECTROOPTICAL DISPLAY ELEMENTS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-04-04 | — | — | US | disclosed |
| EP-0117476-B1 | TETRAHYDROPYRANES | MERCK PATENT GmbH (DE) | 1987-09-16 | — | — | EP | disclosed |
| EP-0117476-A1 | Tetrahydropyranes | MERCK PATENT GmbH (DE) | 1984-09-05 | — | — | EP | disclosed |