Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13263379 | 1.00 | CYP2C9 (0.50) | CYP2C9RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10554603 | 1.00 | CYP2C9 (0.50) | CYP2C9RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL963660 | 0.82 | CYP2C9 (0.49) | CYP2C9RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL963659 | 0.82 | CYP2C9 (0.49) | CYP2C9RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13590567 | 0.82 | CYP2C9 (0.49) | CYP2C9RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1194632 | 0.80 | CYP2C9 (0.47) | CYP2C9RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1194631 | 0.80 | CYP2C9 (0.47) | CYP2C9RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21882563 | 0.80 | ALDH1A1 (0.53) | CYP2C9KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL1195362 | 0.79 | CYP2C9 (0.46) | CYP2C9RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1195361 | 0.79 | CYP2C9 (0.46) | CYP2C9RAB9AKMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4847256-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1989-07-11 | — | — | US | disclosed |
| EP-0264773-A1 | 4,5-dihydro and 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidines | AMERICAN CYANAMID COMPANY (US) | 1988-04-27 | — | — | EP | disclosed |