Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57798 | 0.97 | AKT1 (0.46) | AKT1ALDH1A1CYP19A1CYP11B2CYP1A2 | |
| SCHEMBL7935762 | 0.95 | AKT1 (0.44) | AKT1ALDH1A1CYP19A1CYP11B2CYP1A2 | |
| SCHEMBL11442993 | 0.95 | AKT1 (0.44) | AKT1ALDH1A1CYP19A1CYP11B2CYP1A2 | |
| (Z)-1,2-Diphenylethene SCHEMBL9544908 | 0.87 | MAOB (0.44) | AKT1ALDH1A1CYP19A1CYP11B2CYP1A2 | |
| Alcohol SCHEMBL9291969 | 0.87 | AKT1 (0.39) | AKT1ALDH1A1CYP19A1CYP11B2CYP1A2 | |
| (Z)-1,2-Diphenylethene SCHEMBL9544912 | 0.87 | MAOB (0.44) | AKT1ALDH1A1CYP19A1CYP11B2CYP1A2 | |
| SCHEMBL5601104 | 0.86 | AKT1 (0.41) | AKT1ALDH1A1CYP19A1CYP11B2CYP1A2 | |
| SCHEMBL5601091 | 0.86 | AKT1 (0.41) | AKT1ALDH1A1CYP19A1CYP11B2CYP1A2 | |
| SCHEMBL11472197 | 0.85 | TSHR (0.56) | AKT1ALDH1A1CYP2C9TSHRCES2 | |
| SCHEMBL11472193 | 0.85 | TSHR (0.56) | AKT1ALDH1A1CYP2C9TSHRCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4845201-A | Process for producing organolanthanides, the resultant compounds and their use | INSTITUT FRANCAIS DU PETROLE (FR) | 1989-07-04 | — | — | US | disclosed |
| EP-0277061-A2 | Process for obtaining organolantharides, compounds so obtained and their use | Institut Français du Pétrole (FR) | 1988-08-03 | — | — | EP | disclosed |