(Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

SCHEMBL9544912

C(=Cc1ccccc1)c1ccccc1.C=CC=C(c1ccccc1)c1ccccc1

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.44
PLIN1 O60240 2/20 0.44
LMNA P02545 2/20 0.44
MAPT P10636 2/20 0.44
RECQL P46063 2/20 0.44
PLIN5 Q00G26 2/20 0.44
ABHD5 Q8WTS1 2/20 0.44
BCHE P06276 1/20 0.44
TNFRSF1A P19438 1/20 0.44
ACHE P22303 1/20 0.44
CYP1B1 Q16678 1/20 0.44
HDAC1 Q13547 2/20 0.41
ALDH1A1 P00352 2/20 0.41
TSHR P16473 1/20 0.41
TRPA1 O75762 1/20 0.41
CYP19A1 P11511 3/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
NFE2L2 Q16236 1/20 0.40
MAOA P21397 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL9544908 1.00 MAOB (0.44) MAOBPLIN1LMNAMAPTRECQL
SCHEMBL7059907 0.92 MAOB (0.54) MAOBPLIN1LMNAMAPTRECQL
SCHEMBL7059909 0.92 MAOB (0.54) MAOBPLIN1LMNAMAPTRECQL
SCHEMBL57798 0.89 AKT1 (0.46) MAPTRECQLALDH1A1TSHRCYP19A1
SCHEMBL7935762 0.87 AKT1 (0.44) ALDH1A1TSHRCYP19A1NFE2L2ESR1
SCHEMBL11442993 0.87 AKT1 (0.44) MAPTALDH1A1TSHRTRPA1CYP19A1
SCHEMBL10555014 0.87 AKT1 (0.44) ALDH1A1TSHRCYP19A1NFE2L2ESR1
Alcohol SCHEMBL9291969 0.79 AKT1 (0.39) LMNAMAPTHDAC1ALDH1A1CYP19A1
SCHEMBL5601091 0.78 AKT1 (0.41) MAPTALDH1A1TSHRCYP19A1ESR1
SCHEMBL5601104 0.78 AKT1 (0.41) MAPTALDH1A1TSHRCYP19A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8835865-B2 Mixed crystal organic scintillators LAWRENCE LIVERMORE NATIONAL SECURITY, LLC. (US) 2014-09-16 US disclosed
US-20140124677-A1 MIXED CRYSTAL ORGANIC SCINTILLATORS LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (US) 2014-05-08 US disclosed
WO-1993010753-A1 UVA-ABSORBING SUNSCREEN METAL COMPLEXES RICHARDSON-VICKS, INC. (US) 1993-06-10 WO disclosed