Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 9/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10558916 | 0.90 | GABRA1 (0.37) | MGLLGABRA1GABRB2HCAR1 | |
| SCHEMBL10558657 | 0.85 | NR1H2 (0.40) | — | |
| SCHEMBL10557575 | 0.81 | MEN1 (0.34) | P2RX4 | |
| SCHEMBL10561265 | 0.80 | P2RX4 (0.33) | P2RX4 | |
| SCHEMBL10560178 | 0.80 | P2RX4 (0.41) | P2RX4P2RX1P2RX3 | |
| SCHEMBL10559856 | 0.80 | P2RX4 (0.33) | P2RX4THRBTSHR | |
| SCHEMBL10559786 | 0.79 | P2RX4 (0.32) | P2RX4 | |
| SCHEMBL10561285 | 0.78 | P2RX4 (0.39) | P2RX4P2RX1P2RX3 | |
| SCHEMBL10560234 | 0.78 | P2RX4 (0.38) | P2RX4P2RX1P2RX3 | |
| SCHEMBL10560185 | 0.74 | NR1H2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4803269-A | ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1989-02-07 | — | — | US | disclosed |
| US-4707473-A | ANTIINFLAMMATORY AGENTS | SYNTEX (U.S.A.) INC. (US) | 1987-11-17 | — | — | US | disclosed |