Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8998402 | 0.89 | EPHX2 (0.48) | EPHX2NR1H4MEN1ALDH1A1MAPT | |
| SCHEMBL8998285 | 0.88 | EPHX2 (0.44) | EPHX2NR1H4CYSLTR2CYSLTR1NOX1 | |
| SCHEMBL9479093 | 0.87 | EPHX2 (0.53) | EPHX2NR1H4CYSLTR2CYSLTR1 | |
| SCHEMBL8998208 | 0.87 | EPHX2 (0.51) | EPHX2NR1H4MEN1ALDH1A1MAPT | |
| SCHEMBL8998273 | 0.85 | EPHX2 (0.66) | EPHX2NR1H4MEN1ALDH1A1MAPT | |
| SCHEMBL10561346 | 0.84 | EPHX2 (0.57) | EPHX2NR1H4MEN1ALDH1A1MAPT | |
| SCHEMBL9491290 | 0.83 | EPHX2 (0.55) | EPHX2NR1H4TSHRCYSLTR2CYSLTR1 | |
| SCHEMBL10558787 | 0.81 | CYSLTR2 (0.50) | EPHX2NR1H4CYSLTR2CYSLTR1 | |
| SCHEMBL19083763 | 0.81 | EPHX2 (0.57) | EPHX2NR1H4MEN1ALDH1A1MAPT | |
| SCHEMBL9479106 | 0.81 | EPHX2 (0.51) | EPHX2NR1H4MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4837235-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ICI AMERICAS INC. (US) | 1989-06-06 | — | — | US | disclosed |