Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 13/20 | 0.50 |
| ▸ | CYSLTR1 | Q9Y271 | 13/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9479001 | 0.86 | CYSLTR1 (0.60) | CYSLTR2CYSLTR1EPHX2NR1H4 | |
| SCHEMBL8998153 | 0.84 | EPHX2 (0.66) | CYSLTR2CYSLTR1EPHX2NR1H4 | |
| SCHEMBL10368754 | 0.84 | EPHX2 (0.65) | CYSLTR2CYSLTR1EPHX2NR1H4 | |
| SCHEMBL8998286 | 0.83 | EPHX2 (0.56) | CYSLTR2CYSLTR1EPHX2NR1H4 | |
| SCHEMBL10562486 | 0.82 | CYSLTR1 (0.73) | CYSLTR2CYSLTR1EPHX2 | |
| SCHEMBL10557006 | 0.81 | EPHX2 (0.49) | CYSLTR2CYSLTR1EPHX2NR1H4 | |
| SCHEMBL10367789 | 0.80 | CYSLTR1 (0.67) | CYSLTR2CYSLTR1EPHX2NR1H4 | |
| SCHEMBL8998132 | 0.80 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1EPHX2NR1H4 | |
| SCHEMBL10369577 | 0.79 | CYSLTR2 (0.59) | CYSLTR2CYSLTR1EPHX2NR1H4 | |
| SCHEMBL8998285 | 0.79 | EPHX2 (0.44) | CYSLTR2CYSLTR1EPHX2NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4837235-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | ICI AMERICAS INC. (US) | 1989-06-06 | — | — | US | disclosed |
| EP-0227241-A2 | Medicinal indole and indazole keto sulphone derivatives | ZENECA INC. (US) | 1987-07-01 | — | — | EP | disclosed |