Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | GRM2 | Q14416 | 16/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10558022 | 0.85 | CYP3A4 (0.83) | CYP3A4GRM2PKM | |
| SCHEMBL10560245 | 0.84 | CYP3A4 (0.67) | CYP3A4GRM2 | |
| SCHEMBL10561478 | 0.83 | CYP3A4 (0.65) | CYP3A4GRM2PKM | |
| SCHEMBL6736092 | 0.80 | GRM2 (0.57) | CYP3A4GRM2 | |
| SCHEMBL10561440 | 0.80 | CYP3A4 (0.58) | CYP3A4PKM | |
| SCHEMBL10560884 | 0.80 | CYP3A4 (0.61) | CYP3A4GRM2 | |
| SCHEMBL6733980 | 0.77 | GRM2 (0.58) | GRM2 | |
| SCHEMBL9634037 | 0.75 | CYP3A4 (0.64) | CYP3A4PKM | |
| SCHEMBL6730852 | 0.74 | GRM2 (0.57) | GRM2 | |
| SCHEMBL10562540 | 0.74 | CYP3A4 (0.69) | CYP3A4GRM2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4874775-A | INHIBIT PHYTOPATHOGENS | ELI LILLY AND COMPANY (US) | 1989-10-17 | — | — | US | disclosed |
| EP-0206581-A2 | Agriculturally-useful sulfonamides | ELI LILLY AND COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |