Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28469226 | 0.77 | TSHR (0.40) | TSHRTHRBHSD17B10DNM1ALDH1A1 | |
| SCHEMBL1964779 | 0.76 | TSHR (0.44) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL28468068 | 0.74 | TSHR (0.42) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL29012478 | 0.69 | TSHR (0.50) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL28253481 | 0.69 | TSHR (0.50) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL24370114 | 0.67 | THRB (0.57) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL1221777 | 0.67 | TSHR (0.57) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL867481 | 0.67 | TSHR (0.57) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL201749 | 0.67 | THRB (0.57) | TSHRTHRBHSD17B10CES2CTSL | |
| SCHEMBL20634256 | 0.67 | TSHR (0.57) | TSHRTHRBHSD17B10CES2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4828753-A | Storage-stable organic solutions of polyisocyanates | RHONE-POULENC SPECIALITIES CHIMIQUES (FR) | 1989-05-09 | — | — | US | claimed |
| US-4828753-A | Storage-stable organic solutions of polyisocyanates | RHONE-POULENC SPECIALITIES CHIMIQUES (FR) | 1989-05-09 | — | — | US | disclosed |