Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | DRD5 | P21918 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10460536 | 0.94 | HTR2A (0.58) | HTR2AHTR1ADRD2DRD1DRD5 | |
| SCHEMBL10556534 | 0.94 | KMT2A (0.58) | DRD2KMT2AMEN1ALDH1A1HRH3 | |
| SCHEMBL10461614 | 0.92 | HTR2A (0.47) | HTR2AHTR1ADRD2DRD1DRD5 | |
| Fumaric Acid SCHEMBL10461600 | 0.91 | HTR2A (0.53) | HTR2AKMT2A | |
| Fumaric Acid SCHEMBL10461598 | 0.91 | HTR2A (0.53) | HTR2AKMT2A | |
| SCHEMBL10459423 | 0.89 | HRH3 (0.56) | KMT2AALDH1A1HRH3 | |
| SCHEMBL10563296 | 0.88 | HTR2A (0.53) | HTR2AHTR1ADRD2DRD1DRD5 | |
| SCHEMBL10560025 | 0.88 | DRD2 (0.69) | HTR2AHTR1ADRD2DRD1DRD5 | |
| SCHEMBL10559724 | 0.88 | HTR2A (0.56) | HTR2AHTR1ADRD2DRD1DRD5 | |
| Water SCHEMBL10461590 | 0.88 | HRH3 (0.55) | KMT2AALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4810713-A | Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl groups used in a method for allergy treatment | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-03-07 | — | — | US | claimed |
| EP-0235463-A2 | N-substituted-arylalkyl and arylalkylene piperidines as cardiovascular antihistaminic and antisecretory agents | A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) (US) | 1987-09-09 | — | — | EP | claimed |