Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.73 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | VDR | P11473 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP3A5 | P20815 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31285576 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1CYP3A4CYP2C19GAA | |
| SCHEMBL8877012 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1CYP3A4CYP2C19GAA | |
| SCHEMBL6000027 | 0.84 | KDM4E (0.73) | KDM4EGAAMEN1KMT2ALMNA | |
| SCHEMBL8038878 | 0.80 | GAA (0.68) | KDM4ECYP19A1VDRALDH1A1CYP3A4 | |
| SCHEMBL10557581 | 0.79 | CFTR (0.66) | KDM4ECYP19A1VDRCYP3A4CYP2C19 | |
| SCHEMBL2931121 | 0.79 | ALDH1A1 (0.62) | KDM4EALDH1A1CYP3A4CYP2C19GAA | |
| SCHEMBL11205766 | 0.79 | ALDH1A1 (0.62) | KDM4EALDH1A1CYP3A4CYP2C19GAA | |
| SCHEMBL10389939 | 0.79 | ALDH1A1 (0.62) | KDM4EALDH1A1CYP3A4CYP2C19GAA | |
| SCHEMBL19323939 | 0.76 | KDM4E (0.61) | KDM4ECYP3A4CYP2C19GAAMAPK1 | |
| Hydrochloric Acid SCHEMBL11568531 | 0.76 | KDM4E (0.50) | KDM4ECYP19A1VDRCYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4874775-A | INHIBIT PHYTOPATHOGENS | ELI LILLY AND COMPANY (US) | 1989-10-17 | — | — | US | disclosed |
| EP-0206581-A2 | Agriculturally-useful sulfonamides | ELI LILLY AND COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |
| CN-86103621-A | The method of the sulphonamide of preparation agriculturally useful | — | 1986-12-10 | — | — | CN | disclosed |
| US-4501746-A | HERBICIDES; PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1985-02-26 | — | — | US | disclosed |