Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.59 |
| ▸ | CTSK | P43235 | 4/20 | 0.59 |
| ▸ | CTSS | P25774 | 3/20 | 0.59 |
| ▸ | CTSB | P07858 | 3/20 | 0.59 |
| ▸ | ECE1 | P42892 | 2/20 | 0.58 |
| ▸ | MME | P08473 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 2/20 | 0.54 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 3/20 | 0.53 |
| ▸ | CASP1 | P29466 | 2/20 | 0.53 |
| ▸ | CASP7 | P55210 | 2/20 | 0.53 |
| ▸ | CASP6 | P55212 | 2/20 | 0.53 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.53 |
| ▸ | CASP9 | P55211 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alanine SCHEMBL5485711 | 0.96 | CTSL (0.58) | CTSLCTSKCTSSCTSBECE1 | |
| SCHEMBL2978398 | 0.96 | CTSL (0.63) | CTSLCTSKCTSSCTSBECE1 | |
| SCHEMBL8671882 | 0.96 | CTSL (0.63) | CTSLCTSKCTSSCTSBECE1 | |
| SCHEMBL1287168 | 0.96 | CTSL (0.63) | CTSLCTSKCTSSCTSBECE1 | |
| SCHEMBL220569 | 0.96 | CTSL (0.63) | CTSLCTSKCTSSCTSBECE1 | |
| Valine SCHEMBL5917142 | 0.93 | CTSL (0.56) | CTSLCTSKCTSSCTSBECE1 | |
| Glycine SCHEMBL8365362 | 0.92 | CTSL (0.57) | CTSLCTSKCTSSCTSBECE1 | |
| SCHEMBL6272667 | 0.90 | ECE1 (0.64) | CTSLCTSKCTSSCTSBECE1 | |
| SCHEMBL7378851 | 0.90 | ECE1 (0.64) | CTSLCTSKCTSSCTSBECE1 | |
| SCHEMBL20854293 | 0.90 | CTSL (0.57) | CTSLCTSKCTSSCTSBECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4855454-A | CHEMICAL INTERMEDIATES; SWEETENERS | PFIZER INC. (US) | 1989-08-08 | — | — | US | disclosed |