Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10562556 | 1.00 | RARB (0.67) | RARBRAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL10505457 | 1.00 | RARB (0.67) | RARBRAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL4801321 | 1.00 | RARB (0.67) | RARBRAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL10505564 | 1.00 | RARB (0.67) | RARBRAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL4800256 | 1.00 | RARB (0.67) | RARBRAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL10555573 | 1.00 | RARB (0.67) | RARBRAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL5354918 | 0.98 | RARB (0.64) | RARBRAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL10501562 | 0.97 | RARB (0.63) | RARBRAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL10501354 | 0.97 | RARB (0.63) | RARBRAB9ASMN1; SMN2MAPTKDM4E | |
| SCHEMBL8448885 | 0.97 | RARB (0.62) | RARBRAB9ASMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126949-B1 | FLUORINE-CONTAINING PYRIMIDINE DERIVATIVES | MERCK PATENT GmbH (DE) | 1989-09-27 | — | — | EP | disclosed |
| US-4812258-A | LIQUID CRYSTAL DIELECTRICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-03-14 | — | — | US | disclosed |
| EP-0126949-A2 | Fluorine-containing pyrimidine derivatives | MERCK PATENT GmbH (DE) | 1984-12-05 | — | — | EP | disclosed |