Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 11/20 | 0.53 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.50 |
| ▸ | FADS1 | O60427 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10561016 | 0.86 | PDE4A (0.41) | SCDNPBWR1 | |
| SCHEMBL10555120 | 0.84 | NPC1 (0.47) | NPBWR1 | |
| SCHEMBL2455602 | 0.83 | PDE4A (0.57) | SCD | |
| SCHEMBL10556840 | 0.83 | PDE4A (0.41) | SCDNPBWR1 | |
| Hydrochloric Acid SCHEMBL10555631 | 0.82 | NPC1 (0.46) | SCDNPBWR1 | |
| SCHEMBL10556845 | 0.81 | PDE4A (0.42) | — | |
| SCHEMBL10559564 | 0.81 | NPBWR1 (0.51) | NPBWR1 | |
| SCHEMBL2455601 | 0.78 | PDE4A (0.64) | SCD | |
| SCHEMBL10558722 | 0.77 | MAPT (0.62) | — | |
| Hydrochloric Acid SCHEMBL10560128 | 0.77 | PDE4A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863945-A | CARDIOVASCULAR DISORDERS | BOEHRINGER MANNHEIM GMBH (DE) | 1989-09-05 | — | — | US | disclosed |
| EP-0271040-A2 | Pyrrolobenzimidazoles, process for their preparation, and medicaments | Roche Diagnostics GmbH (DE) | 1988-06-15 | — | — | EP | disclosed |