Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 5/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10557397 | 0.86 | RARB (0.57) | RARBKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL9850104 | 0.85 | ALDH1A1 (0.54) | RARBKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL8857747 | 0.82 | RARB (0.60) | RARBKDM4EALDH1A1HSD17B10RARA | |
| SCHEMBL8857746 | 0.82 | RARB (0.60) | RARBKDM4EALDH1A1HSD17B10RARA | |
| SCHEMBL10986616 | 0.82 | RARB (0.70) | RARBKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL10978132 | 0.82 | RARB (0.70) | RARBKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL10983870 | 0.82 | RARB (0.70) | RARBKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL10977177 | 0.82 | RARB (0.70) | RARBKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL10982563 | 0.82 | RARB (0.70) | RARBKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL9398735 | 0.82 | RARB (0.70) | RARBKDM4EMEN1USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126949-B1 | FLUORINE-CONTAINING PYRIMIDINE DERIVATIVES | MERCK PATENT GmbH (DE) | 1989-09-27 | — | — | EP | disclosed |
| US-4812258-A | LIQUID CRYSTAL DIELECTRICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-03-14 | — | — | US | disclosed |
| EP-0126949-A2 | Fluorine-containing pyrimidine derivatives | MERCK PATENT GmbH (DE) | 1984-12-05 | — | — | EP | disclosed |