Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 16/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6733821 | 0.83 | GRM2 (0.61) | GRM2GAALMNASMN1; SMN2 | |
| SCHEMBL10561547 | 0.82 | GRM2 (0.60) | GRM2GAALMNASMN1; SMN2CYP3A4 | |
| SCHEMBL6732098 | 0.82 | GRM2 (0.60) | GRM2GAALMNASMN1; SMN2CYP3A4 | |
| SCHEMBL10560268 | 0.82 | CYP3A4 (0.54) | GRM2SMN1; SMN2CYP3A4 | |
| SCHEMBL6732221 | 0.81 | GRM2 (0.80) | GRM2GAALMNASMN1; SMN2 | |
| SCHEMBL6733966 | 0.81 | GRM2 (0.60) | GRM2GAA | |
| SCHEMBL6735454 | 0.81 | GRM2 (0.71) | GRM2GAALMNASMN1; SMN2 | |
| SCHEMBL10556648 | 0.80 | CYP3A4 (0.67) | GRM2GAALMNASMN1; SMN2CYP3A4 | |
| SCHEMBL6731259 | 0.79 | GRM2 (0.66) | GRM2GAALMNASMN1; SMN2CYP3A4 | |
| SCHEMBL10561180 | 0.79 | LMNA (0.68) | GRM2GAALMNASMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4874775-A | INHIBIT PHYTOPATHOGENS | ELI LILLY AND COMPANY (US) | 1989-10-17 | — | — | US | disclosed |
| EP-0206581-A2 | Agriculturally-useful sulfonamides | ELI LILLY AND COMPANY (US) | 1986-12-30 | — | — | EP | disclosed |