Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6642393 | 0.78 | HSD11B1 (0.42) | HSD11B1KMT2AALDH1A1TSHR | |
| SCHEMBL3494879 | 0.76 | HSD11B1 (0.46) | HSD11B1KMT2AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL1648325 | 0.76 | KDM4E (0.49) | KMT2ACYP1A2MAPTKDM4EALDH1A1 | |
| SCHEMBL1902043 | 0.76 | ELANE (0.46) | HSD11B1KMT2ACYP1A2CYP3A4MAPT | |
| SCHEMBL10015547 | 0.75 | NCEH1 (0.53) | HSD11B1CYP1A2CYP3A4MAPTCYP2C19 | |
| SCHEMBL3379105 | 0.75 | NPSR1 (0.40) | CYP1A2CYP3A4MAPTCYP2C19KDM4E | |
| SCHEMBL3379111 | 0.75 | NPSR1 (0.40) | KDM4EALDH1A1LMNADRD2HPGD | |
| SCHEMBL3377822 | 0.75 | MAPT (0.42) | KMT2ACYP1A2CYP3A4MAPTCYP2C19 | |
| SCHEMBL3377816 | 0.75 | KMT2A (0.39) | KMT2ACYP1A2CYP3A4MAPTCYP2C19 | |
| SCHEMBL14270838 | 0.75 | HSD11B1 (0.45) | HSD11B1CYP3A4CYP2C19KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110015401-A1 | Metal-Catalyzed Carbon-Fluorine Bond Formation | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015401-A1 | Metal-Catalyzed Carbon-Fluorine Bond Formation | FLI1, VGF, GMFG | HSD11B1 3639/4885KMT2A 196/4885THRB 4731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.