Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY5 | O95622 | 2/20 | 0.59 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.59 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.59 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.59 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.59 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.59 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.59 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.59 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 5/20 | 0.37 |
| ▸ | HTR2B | P41595 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10350885 | 0.98 | ADCY5 (0.57) | ADCY5ADCY6ADCY3ADCY9ADCY8 | |
| SCHEMBL10567329 | 0.80 | ADCY6 (0.41) | ADCY5ADCY6ADCY3ADCY9ADCY8 | |
| Hydrochloric Acid SCHEMBL10350476 | 0.79 | ADCY6 (0.39) | ADCY5ADCY6ADCY3ADCY9ADCY8 | |
| SCHEMBL10564212 | 0.79 | HTR2C (0.43) | ADCY5ADCY6ADCY3ADCY9ADCY8 | |
| SCHEMBL10561747 | 0.78 | ADCY6 (0.53) | ADCY5ADCY6ADCY3ADCY9ADCY8 | |
| Hydrochloric Acid SCHEMBL10564211 | 0.77 | HTR2C (0.42) | ADCY5ADCY6ADCY3ADCY9ADCY8 | |
| Bromide SCHEMBL10561857 | 0.77 | ADCY6 (0.52) | ADCY5ADCY6ADCY3ADCY9ADCY8 | |
| SCHEMBL5793449 | 0.76 | ADCY6 (1.00) | ADCY5ADCY6ADCY3ADCY9ADCY8 | |
| Hydrochloric Acid SCHEMBL10350543 | 0.75 | HTR2C (0.54) | ADCY5ADCY6ADCY3ADCY9ADCY8 | |
| Bromide SCHEMBL11167892 | 0.74 | ADCY6 (0.95) | ADCY5ADCY6ADCY3ADCY9ADCY8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4824839-A | Sulfinyl and sulfonyl substituted 2,3,4,5 tetrahydro-1H-3-benzazepines and their use in treating gastrointestinal motility disorders | SMITHKLINE BECKMAN CORPORATION (US) | 1989-04-25 | — | — | US | disclosed |