Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 16/20 | 0.65 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367742 | 0.84 | CYP19A1 (0.61) | CYP19A1CYP11B1MEN1KMT2APOLB | |
| SCHEMBL10508502 | 0.80 | CYP19A1 (0.65) | CYP19A1CYP11B1MEN1KMT2APOLB | |
| SCHEMBL10564644 | 0.80 | CYP19A1 (0.46) | CYP19A1CYP11B1HSP90AA1CYP3A4 | |
| SCHEMBL11365523 | 0.77 | CYP19A1 (0.71) | CYP19A1CYP11B1MEN1KMT2APOLB | |
| SCHEMBL10565622 | 0.77 | PDE2A (0.44) | CYP19A1CYP11B1MEN1KMT2APOLB | |
| SCHEMBL7310662 | 0.75 | CYP19A1 (0.63) | CYP19A1CYP11B1MEN1KMT2A | |
| SCHEMBL10509139 | 0.75 | CYP19A1 (0.58) | CYP19A1CYP11B1KMT2A | |
| SCHEMBL11258462 | 0.75 | CYP19A1 (0.67) | CYP19A1CYP11B1POLBHSP90AA1CYP3A4 | |
| SCHEMBL10875632 | 0.72 | POLB (0.60) | CYP19A1CYP11B1MEN1KMT2APOLB | |
| SCHEMBL10767277 | 0.72 | CYP19A1 (0.63) | CYP19A1CYP11B1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194064-A2 | Azolyl substituted aralkyl compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-09-10 | — | — | EP | claimed |
| US-4829074-A | INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-09 | — | — | US | disclosed |
| EP-0194064-A2 | Azolyl substituted aralkyl compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-09-10 | — | — | EP | disclosed |