Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 12/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10564644 | 0.82 | CYP19A1 (0.46) | PDE2ACYP19A1HSP90AA1CYP3A4CYP11B1 | |
| SCHEMBL10565254 | 0.77 | CYP19A1 (0.65) | CYP19A1POLBHSP90AA1CYP3A4MEN1 | |
| SCHEMBL10565684 | 0.77 | CYP19A1 (0.40) | PDE2ACYP19A1NPBWR1MCHR1POLB | |
| SCHEMBL10567440 | 0.76 | CYP17A1 (0.46) | PDE2ACYP19A1ALDH1A1NPBWR1MCHR1 | |
| SCHEMBL10565630 | 0.76 | PDE2A (0.40) | PDE2ACYP19A1ALDH1A1NPBWR1MCHR1 | |
| SCHEMBL9467692 | 0.76 | POLB (0.38) | PDE2ACYP19A1ALDH1A1POLBHSP90AA1 | |
| SCHEMBL9362897 | 0.76 | CYP19A1 (0.43) | CYP19A1ALDH1A1POLBHSP90AA1CYP3A4 | |
| SCHEMBL9467685 | 0.76 | POLB (0.38) | PDE2ACYP19A1ALDH1A1POLBHSP90AA1 | |
| SCHEMBL6947959 | 0.76 | MEN1 (0.46) | CYP19A1ALDH1A1POLBHSP90AA1CYP3A4 | |
| SCHEMBL10565696 | 0.75 | CYP19A1 (0.41) | PDE2ACYP19A1ALDH1A1NPBWR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194064-A2 | Azolyl substituted aralkyl compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-09-10 | — | — | EP | claimed |
| US-4829074-A | INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-09 | — | — | US | disclosed |
| EP-0194064-A2 | Azolyl substituted aralkyl compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-09-10 | — | — | EP | disclosed |