Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.39 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | KDM4B | O94953 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31275319 | 0.90 | PDE10A (0.38) | PSMB5HRH4PSDNPC1RAB9A | |
| SCHEMBL5534390 | 0.82 | KDM5A (0.31) | PSMB5 | |
| SCHEMBL27268161 | 0.81 | DRD4 (0.40) | HRH4 | |
| SCHEMBL12250775 | 0.79 | HRH4 (0.42) | PSMB5CTSKCTSSHRH4TLR8 | |
| SCHEMBL3214532 | 0.77 | HRH4 (0.41) | CTSKCTSSHRH4PSDTLR8 | |
| SCHEMBL19771672 | 0.77 | HRH4 (0.41) | CTSKCTSSHRH4PSDTLR8 | |
| SCHEMBL3229097 | 0.75 | HRH4 (0.42) | CTSKCTSSHRH4PSDTLR8 | |
| SCHEMBL8321238 | 0.74 | HRH4 (0.59) | HRH4 | |
| SCHEMBL18557016 | 0.74 | NPC1 (0.42) | PSMB5NPC1RAB9AL3MBTL1CASP3 | |
| SCHEMBL22271218 | 0.74 | NPC1 (0.42) | PSMB5NPC1RAB9AL3MBTL1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4824846-A | FUNGICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-04-25 | — | — | US | disclosed |
| EP-0237963-A2 | 2-Azolylmethyl-2-aryl-1,3-dioxolanes and their salts, processes for their preparation, compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-23 | — | — | EP | disclosed |