SCHEMBL5534390

SCHEMBL5534390

Cc1cc(Cl)nc(C2C[CH]CCC2)c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 1/20 0.31
PSMB5 P28074 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10567415 0.82 PSMB5 (0.41) PSMB5
SCHEMBL31275319 0.79 PDE10A (0.38) PSMB5
SCHEMBL27268161 0.71 DRD4 (0.40)
SCHEMBL3542869 0.69
SCHEMBL12250775 0.69 HRH4 (0.42) KDM5APSMB5
SCHEMBL18017246 0.64 NOS3 (0.43) KDM5APSMB5
SCHEMBL165100 0.64
SCHEMBL29097441 0.64 ALDH1A1 (0.41)
SCHEMBL12250833 0.64 HRH4 (0.38) PSMB5
SCHEMBL19510867 0.64 FFAR4 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7262194-B2 Therapeutic agents useful for treating pain EURO-CELTIQUE S.A. 2007-08-28 US disclosed