Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | CD44 | P16070 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | APAF1 | O14727 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP2 | O95551 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31629213 | 0.84 | MEN1 (0.48) | MEN1KMT2ACDC25BPOLBRAB9A | |
| Anthraquinone SCHEMBL27788192 | 0.74 | MEN1 (0.67) | MEN1KMT2ACDC25BMAOBPOLB | |
| SCHEMBL11734129 | 0.73 | MAOB (0.41) | PNMTCD44MAOBKDM4EMAPT | |
| Phentydrone SCHEMBL875187 | 0.73 | MEN1 (0.57) | MEN1KMT2ACDC25BMAOBPOLB | |
| SCHEMBL11724324 | 0.72 | MAOB (0.39) | PNMTCD44MAOBKDM4EMAOA | |
| Anthraquinone SCHEMBL16429363 | 0.70 | MEN1 (0.60) | MEN1KMT2ACDC25BMAOBPOLB | |
| Anthraquinone SCHEMBL11352939 | 0.70 | MEN1 (0.60) | MEN1KMT2ACDC25BMAOBPOLB | |
| Anthraquinone SCHEMBL7915429 | 0.68 | MEN1 (0.86) | MEN1KMT2ACDC25BMAOBPOLB | |
| Anthraquinone SCHEMBL1445042 | 0.68 | MEN1 (0.86) | MEN1KMT2ACDC25BMAOBPOLB | |
| Phentydrone SCHEMBL9628384 | 0.68 | MEN1 (0.50) | MEN1KMT2ACDC25BPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4824852-A | Substituted indole compounds which have useful effects on the central nervous system | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-04-25 | — | — | US | disclosed |
| US-4740602-A | Indole derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1988-04-26 | — | — | US | disclosed |
| EP-0206225-A2 | Indole derivatives | MERCK PATENT GmbH (DE) | 1986-12-30 | — | — | EP | disclosed |