Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | CD44 | P16070 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | FER | P16591 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11884931 | 0.86 | PDGFRA (0.46) | MAOBPDGFRAFERLTKCDK8 | |
| SCHEMBL11774761 | 0.77 | LRRK2 (0.46) | MAOBPDGFRAFERLTKCDK8 | |
| SCHEMBL11724324 | 0.76 | MAOB (0.39) | MAOBPNMTCD44PRCPHTR2C | |
| SCHEMBL10567491 | 0.73 | MEN1 (0.46) | MAOBPNMTCD44PRCPHTR2C | |
| SCHEMBL22478702 | 0.72 | ACVR1 (0.50) | MAOBPDGFRAFERLTKCDK8 | |
| SCHEMBL10734259 | 0.69 | DRD1 (0.54) | MAOBHTR2CMAOACYP3A4KDM4E | |
| SCHEMBL11094326 | 0.68 | PNMT (0.65) | MAOBPNMTCD44PRCPHTR2C | |
| SCHEMBL11654226 | 0.68 | ACVR1 (0.47) | MAOBPDGFRAFERLTKCDK8 | |
| SCHEMBL30118299 | 0.68 | NOS2 (0.43) | MAOBPDGFRAFERLTKCDK8 | |
| SCHEMBL17816635 | 0.66 | LRRK2 (0.59) | MAOBPDGFRAFERLTKCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4002632-A | ANTIDEPRESSANTS | AKZONA INCORPORATED (US) | 1977-01-11 | — | — | US | disclosed |